The competition holders Liverpool are 25 points ahead Manchester City.
Meanwhile, Atlético have found themselves in the midst of a crisis.
They have fallen out of the La Liga title race and their place in the top four has come under considerable threat.
Diego Simeone has craved this title title for years and let’s not forget this is the only thing they are left playing for between now and the end of the season.
Atléti have always been at their best when they play and feel like the whole world is against them. But will they find that on Tuesday night?