Paris Saint-Germain head coach Thomas Tuchel said that Kylian Mbappe's participation is not sure yet as the Frenchman is suffering from chest pains.
The hosts will play without Marco Verratti and Thomas Meunier tonight because both of them were suspended after being booked.
Midfielder Ander Herrera will miss the fixture because of a thigh injury. Thiago Silva and Colin Dagba might not play too because there are fitness doubts.
However, Neymar and Angel Di Maria are both fully fit and probably they will lead the line tonight.
The visitors will be without Reus due to his groin injury. Thomas Delaney probably will miss the game too because he has fitness problems.
The match will be played behind closed doors because of coronavirus.
Paris Saint-Germain have never beaten Borussia in any European competition, they have two draws and one loss. Their first meet at Parc des Princes was back in 2010 and it was a goalless draw between them.
Borussia Dortmund have won three and lost three of their six away Champions League fixtures against French clubs - Auxerre, Marseille and Monaco.
PSG have never progressed further in the Champions League after losing the first leg of a knockout match.
Borussia Dortmund have always progressed to the next stage after winning the first leg.
Neymar has been involved in 37 goals in 27 home Champions League appearances. 20 appearances for Barcelona and 7 for PSG.
Borussia Dortmund striker Erling Haaland is one of the five players who scored 10+ in their debut campaign
Paris Saint-Germain have lost five of their last six Champions League knockout matches, losing each of their last two at the Parc des Princes. The first loss was against Real Madrid in 2018 and the second was against Manchester United in 2019.
Borussia have lost each of their last five away Champions League knockout matches. Their last victory was back in 2014 against Zenit when they were under Jürgen Klopp.